Designing learning environments that attend to individual students and their interactions with one another may seem an impossible task in a course of 20 students, much less a course of more than 700. However, there are a host of simple teaching strategies rooted in research on teaching and learning that can support biology instructors in paying attention to whom they are trying to help learn. These teaching strategies are sometimes referred to as "equitable teaching strategies," whereby striving for "classroom equity" is about teaching all the students in your classroom, not just those who are already engaged, already participating, and perhaps already know the biology being taught. Equity, then, is about striving to structure biology classroom environments that maximize fairness, wherein all students have opportunities to verbally participate, all students can see their personal connections to biology, all students have the time to think, all students can pose ideas and construct their knowledge of biology, and all students are explicitly welcomed into the intellectual discussion of biology. Without attention to the structure of classroom interactions, what can often ensue is a wonderfully designed biology lesson that can be accessed by only a small subset of students in a classroom. So what specific teaching strategies might we instructors, as architects of the learning environment in our classrooms, use to structure the classroom learning environment? This article provides a framework for how these teaching strategies might be most useful to instructors, organized into five sections, representing overarching goals instructors may have for their classrooms.