Researchers on the topic of Interactive Whiteboard (IWB) use in education stress that while important, teachers' mastering of the technological and interactive aspects of the IWB is not enough for its productive use. In order to get the most out of the relatively expensive investment in IWBs, much of the attention has to be given to the student active engagement during the lessons. In a qualitative study, we investigated how students interacted with an IWB during a lesson that was designed based on the principles of guided-inquiry and kinesthetic engagement of learners. Our study used activity theory as a descriptive framework for analysis. The topic of the lessons was Kepler's laws. We have found that students are well adapted to a shift from classical board-like use of the IWB that is predominant in a high school setting to touchscreen-like use, where kinesthetic engagement and creative graphical input play a central role. Students engaged in collaborative sense-making, discovering patterns, setting and testing hypotheses with little intervention by the researcher who was present in class during small group activities. However, we found that appropriate scaffolding by the researcher was very important as it allowed the students to avoid pitfalls of technology use. Such scaffolding requires that the person guiding student work with the IWBs possesses technological, pedagogical, and content knowledge.